Bio-techne – Assay
THE miRNAscope™ ASSAY
The highly specific and sensitive miRNAscope™ Assay has been developed by ACD, a Bio-Techne brand, to detect small RNAs with spatial and morphological context at single-cell resolution. Leveraging our RNAscope™ core technology, the miRNAscope Assay is designed to enable detection of small RNAs including, antisense oligonucleotides (ASOs), microRNAs (miRNAs), small interfering RNAs (siRNAs), and other smaller RNAs of 17-50 bases.
RNAscope™ Multiplex Fluorescent V2 assay with New TSA Vivid™ Dyes
The RNAscope Multiplex Fluorescent v2 assays provides exceptional sensitivity and allows single-molecule detection of up to four RNA targets simultaneously. The significant signal boost provided by simultaneous background noise suppression from patented signal amplification technology for ISH when combined with Tyramide Signal Amplification technology (TSA™) for visualization allows expanded applications such as ISH on FFPE tissues and dual ISH-IHC.
RNAscope™ Multiomic LS Assay
The RNAscope™ Multiomic LS assay enables highly sensitive and specific detection of both RNA and proteins in the same tissue section for a true multiomic spatial assay. Proven class-leading single-molecule RNAscope technology is leveraged to enable simultaneous detection of up to 6 total proteins and RNA targets with single cell resolution.
RNAscope™ Plus small RNA-RNA Fluorescent Assay
Small regulatory RNAs, including miRNAs, are instrumental in regulating human health and have been associated with a wide range of different diseases. Oligonucleotide therapies, including antisense oligonucleotides (ASOs) and RNA interference (RNAi), represent a unique class of gene therapies that have the potential to provide highly focused, long-lasting therapeutic effects by utilizing similar cellular processes.
Key Features
THE miRNAscope™ ASSAY
- Specificity: Deeper evaluation of target in tissue context
- Speed: Simple and fast workflow with both manual and automated formats to fit your need
- Sensitivity: Spatial context with subcellular resolution
- Ease of use: Hands on support and guidance from experienced in-house scientists
RNAscope™ Multiplex Fluorescent V2 assay with New TSA Vivid™ Dyes
- Simultaneous detection of 4 RNA or 3 RNA + 1 protein targets in FFPE and fixed or fresh frozen tissues.
- The Multiplex Fluorescent V2 assay is enabled with Tyramide Signal Amplification (TSA) detection chemistry which improves sensitivity to detect low abundance targets.
- Re-engineered Tyramide Vivid dyes boost signal intensity and increase ease of target visualization.
- Vivid dyes are the best performing tyramide reagents for the RNAscope Multiplex Fluorescent V2 assay.
RNAscope™ Multiomic LS Assay
- Optimized protease-free multiomic workflow: Maintains your tissue morphology for the most accurate spatial analysis
- Fast and flexible assay design: Detect any RNA transcripts. Any gene. Any species.
- Gold-standard RNAscope detection: Proven performance for FFPE samples and high to low expressing target genes.
RNAscope™ Plus small RNA-RNA Fluorescent Assay
- Unlock the potential to detection 1 small RNA along with up to 3 mRNA targets
- Visualize ASOs, siRNAs, miRNAs, piRNAs and other elusive smRNA sequences with the signal boosting tyramide amplification system (TSA) chemistry.
- Interrogate smRNA biomarkers/therapeutics with cell-specific/morphology markers.
- Assess smRNA therapeutic delivery and biodistribution.
- Add a visual dimension to interrogate heterogeneous issues and evaluate therapeutic efficacy.
RNAscope™ Multiplex Fluorescent V2 assay with New TSA Vivid™ Dyes
RNAscope™ Plus small RNA-RNA Fluorescent Assay
Bio-Techne includes the following brands: ACD, Asuragen, ExosomeDx, Lunaphore, Novus Biologicals, ProteinSimple, R&D Systems and Tocris Bioscience. Bio-Techne is headquartered…
