Bio-techne – Automated multiomics on COMET™
COMET™ enables the simultaneous spatial detection of RNA and protein on the same tissue section using RNAscope™ HiPlex Pro and sequential immunofluorescence (seqIF™) with off-the-shelf, non-conjugated primary antibodies.
Description
Thanks to the precise and sensitive detection of both targets, COMET™ provides valuable scientific insights into biomarkers that can be spatially resolved at a single-cell level. The streamlined, end-to-end workflow ensures assay reproducibility and saves time in assay development and execution.
Technical Specifications
| Slide capacity | 4 |
| Maximum imaging area and staining area | Max imaging area: 12.5 mm x 12.5 mm / 0.49 in x 0.49 in Staining area: 21 mm x 21 mm / 0.82 in x 0.82 in |
| Throughput | Measured for a 9 mm x 9 mm imaging area: 20 slides/week for 20-plex protein panel ; 12 slides/week for 40-plex protein panel |
| Microscope: magnification and numerical aperture | 20X / 0.7 NA |
| Image resolution | 0.28 µm/pixel |
| Slide compatibility | Endpoint Kinetic |
| Sample thickness | 3-10 μm |
Key Features
- Maximize reproducibility: Fully automated workflow and precision microfluidics.
- Avoid undesired variability: No upstream antibody conjugations. Perform multiple additional runs on the same slide
- Same-section multiomics: Integrate and correlate spatial RNA and protein data at single-cell level.
- Fully-automated workflow: From target probe hybridization and protein detection to imaging in the same run. Click start and walk away, with up to 4 slides per run.
Additional information
| Applications | Additive manufacturing, Back-end, Back-end Front-end, Beverage preparation, Cable and electrical, Chemical characterization, Chemical characterization Chromatography(MY), Chemical characterization Consumables, Chemical characterization Data Integration and Management System(MY) General lab equipment Life sciences Physical characterization, Chemical characterization Data Integration and Management System(MY) General lab equipment Physical characterization Life sciences, Chemical characterization General lab equipment, Chemical characterization Life sciences, Chemical characterization Oil and gas testing(MY), Chemical characterization Physical characterization, Chemical characterization Sample preparation, Chemical characterization Test and Measurement Equipment(MY), Cleaning, Coding, Consumables, Consumables Chemical characterization, Consumables General lab equipment, Consumables General lab equipment Life sciences, Consumables Life sciences, Consumables Physical characterization, Converting, Diagnostics, DNA analysis, Engines, Environmental technologies, Environmental technologies Power generation, Fine Line Aerosol Printing, Flexible packaging, Flexible packaging Prime labels, Flexible packaging Print auxiliaries and consumables, Flow Cytometry, Food preparation, Food processing, Front-end, Gear cutting and measuring, Gear cutting and measuring Metal cutting and forming, General lab equipment, General lab equipment Life sciences, General lab equipment Life sciences Physical characterization, General lab equipment Process control(MY), General lab equipment Sample preparation, Genlab, Heat treatment, Heating, IAP others, IMS Others, Inline handling, Inline router, IOT Others, Life sciences, Life sciences Consumables, Life sciences General lab equipment, Life sciences General lab equipment Physical characterization, Life sciences Physical characterization Consumables, Metal cutting and forming, Metal cutting and forming Others, Metal cutting and forming Testing and measuring, Metals, Microelectronics, Microelectronics others, Microelectronics Solar cell manufacturing, Microscopy, Oil and gas testing(MY) Physical characterization, OMICS, Others, others Microelectronics, Packaging, PCB Assembly, PCB Assembly Solar cell manufacturing, Pha, Physical characterization, Physical characterization F&B, Physical characterization Life sciences, Physical characterization Physical characterization, Plasma surface cleaning, Power generation, PPC Print auxiliaries and consumables, PPS(MY), Print auxiliaries and consumables, Print auxiliaries and consumables Prime labels, Protein Analysis, Pumps, R&D, Refrigeration, RNA analysis, Sample preparation, Sample preparation Chemical characterization, Sample preparation General lab equipment, Seam sealing, Semicon Back End, SMT, Solar cell manufacturing, Solar cell manufacturing Modules manufacturing, Storage systems, Testing and measuring, Testing and measuring Metal cutting and forming, Wire harnessing |
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| Solutions | Spatial Biology |
| Markets | Philippines |
