Bio-techne – Automated multiomics on COMET™
COMET™ enables the simultaneous spatial detection of RNA and protein on the same tissue section using RNAscope™ HiPlex Pro and sequential immunofluorescence (seqIF™) with off-the-shelf, non-conjugated primary antibodies.
Thanks to the precise and sensitive detection of both targets, COMET™ provides valuable scientific insights into biomarkers that can be spatially resolved at a single-cell level. The streamlined, end-to-end workflow ensures assay reproducibility and saves time in assay development and execution.
Technical Specifications
| Slide capacity | 4 |
| Maximum imaging area and staining area | Max imaging area: 12.5 mm x 12.5 mm / 0.49 in x 0.49 in Staining area: 21 mm x 21 mm / 0.82 in x 0.82 in |
| Throughput | Measured for a 9 mm x 9 mm imaging area: 20 slides/week for 20-plex protein panel ; 12 slides/week for 40-plex protein panel |
| Microscope: magnification and numerical aperture | 20X / 0.7 NA |
| Image resolution | 0.28 µm/pixel |
| Slide compatibility | Endpoint Kinetic |
| Sample thickness | 3-10 μm |
Key Features
- Maximize reproducibility: Fully automated workflow and precision microfluidics.
- Avoid undesired variability: No upstream antibody conjugations. Perform multiple additional runs on the same slide
- Same-section multiomics: Integrate and correlate spatial RNA and protein data at single-cell level.
- Fully-automated workflow: From target probe hybridization and protein detection to imaging in the same run. Click start and walk away, with up to 4 slides per run.
Bio-Techne includes the following brands: ACD, Asuragen, ExosomeDx, Lunaphore, Novus Biologicals, ProteinSimple, R&D Systems and Tocris Bioscience. Bio-Techne is headquartered…
