Showing 1–15 of 17 results

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    Bio-techne – AmplideX Fragile X Dx & Carrier Screen Kit 

    The AmplideX® Fragile X Dx & Carrier Screen Kit is an in vitro diagnostic device intended as an aid in the post-natal diagnosis of fragile X syndrome, and fragile X-associated disorders and for carrier testing in adults of reprodu...

    The AmplideX® Fragile X Dx & Carrier Screen Kit is an in vitro diagnostic device intended as an aid in the post-natal diagnosis of fragile X syndrome, and fragile X-associated disorders and for carrier testing in adults of reproductive age. Based on Asuragen’s unique, PCR-only approach, the assay reliably amplifies and detects all alleles, including low-level mosaics and full mutations, in a simple, streamlined workflow, which includes automated software.
    Requiring only 20ng of DNA from whole blood, the assay provides results within one day.

  • Bio-techne – AmplideX® DM1 Dx Kit 

    The AmplideX DM1 Dx Kit aims to revolutionize the diagnosis of DM1 by providing a simple, sensitive, and streamlined method to analyze DMPK expansions within a single day without the requirement for Southern blot technology.

    The AmplideX DM1 Dx Kit aims to revolutionize the diagnosis of DM1 by providing a simple, sensitive, and streamlined method to analyze DMPK expansions within a single day without the requirement for Southern blot technology.

  • Bio-techne – AmplideX® PCR/CE C9orf72 Kit 

    The Ampli...

    The AmplideX PCR/CE C9orf72 Kit* is a research product for the detection of GGGGCC repeats in the C9orf72 gene. These reagents provide a single-tube PCR approach based on a Repeat-Primed PCR (RP-PCR) design to profile repeat sequences in the C9orf72 gene. 

  • Bio-techne – AmplideX® PCR/CE SMN1/2 Plus Kit

    The AmplideX® SMN1/2 Plus Kit is an in vitro nucleic acid amplification kit intended to aid in the screening of carriers for and diagnosis of spinal muscular atrophy (SMA). The kit is designed for PCR with extracted genomic DNA from hu...

    The AmplideX® SMN1/2 Plus Kit is an in vitro nucleic acid amplification kit intended to aid in the screening of carriers for and diagnosis of spinal muscular atrophy (SMA). The kit is designed for PCR with extracted genomic DNA from human whole blood performed on standard laboratory-validated thermal cyclers, followed by resolution on a general laboratory-validated genetic analyzer or capillary electrophoresis (CE) platform.

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    Bio-techne – Assay

    THE miRNAscope™ ASSAY

    The highly specific and sensitive miRNAscope™ Assay has been developed by ACD, a Bio-Techne brand, to detect small RNAs with spatial and morphological context at single-cell resolution. Leveraging our...

    THE miRNAscope™ ASSAY

    The highly specific and sensitive miRNAscope™ Assay has been developed by ACD, a Bio-Techne brand, to detect small RNAs with spatial and morphological context at single-cell resolution. Leveraging our RNAscope™ core technology, the miRNAscope Assay is designed to enable detection of small RNAs including, antisense oligonucleotides (ASOs), microRNAs (miRNAs), small interfering RNAs (siRNAs), and other smaller RNAs of 17-50 bases.

    RNAscope™ Multiplex Fluorescent V2 assay with New TSA Vivid™ Dyes
    The RNAscope Multiplex Fluorescent v2 assays provides exceptional sensitivity and allows single-molecule detection of up to four RNA targets simultaneously. The significant signal boost provided by simultaneous background noise suppression from patented signal amplification technology for ISH when combined with Tyramide Signal Amplification technology (TSA™) for visualization allows expanded applications such as ISH on FFPE tissues and dual ISH-IHC.

    RNAscope™ Multiomic LS Assay

    The RNAscope™ Multiomic LS assay enables highly sensitive and specific detection of both RNA and proteins in the same tissue section for a true multiomic spatial assay. Proven class-leading single-molecule RNAscope technology is leveraged to enable simultaneous detection of up to 6 total  proteins and RNA targets with single cell resolution.

    RNAscope™ Plus small RNA-RNA Fluorescent Assay

    Small regulatory RNAs, including miRNAs, are instrumental in regulating human health and have been associated with a wide range of different diseases. Oligonucleotide therapies, including antisense oligonucleotides (ASOs) and RNA interference (RNAi), represent a unique class of gene therapies that have the potential to provide highly focused, long-lasting therapeutic effects by utilizing similar cellular processes.

  • Bio-techne – Automated multiomics on COMET™ 

    COMET™ enables the simultaneous spatial detection of RNA and protein on the same tissue section using RNAscope™ HiPlex Pro and sequential immunofluorescence (seqIF™) with off-the-shelf, non-conjugated primary antibodies. Thanks to the precis...

    COMET™ enables the simultaneous spatial detection of RNA and protein on the same tissue section using RNAscope™ HiPlex Pro and sequential immunofluorescence (seqIF™) with off-the-shelf, non-conjugated primary antibodies. Thanks to the precise and sensitive detection of both targets, COMET™ provides valuable scientific insights into biomarkers that can be spatially resolved at a single-cell level. The streamlined, end-to-end workflow ensures assay reproducibility and saves time in assay development and execution.

  • Bio-techne – Classical Culture Media & Balanced Salt Solutions

    Providing ready-to-use products for cell culture, including essential options like DMEM and HBSS, ensures consistent and reliable results and supports optimal cell growth and experimental reproducibility​.

    Providing ready-to-use products for cell culture, including essential options like DMEM and HBSS, ensures consistent and reliable results and supports optimal cell growth and experimental reproducibility​.

    Dulbecco’s Modified Eagle’s Medium (DMEM), a modification of Eagle’s BME, is widely used for a range of mammalian cell culture applications. In comparison with BME, it contains a four-fold higher concentration of amino acids, vitamins, and additional components. A variety of DMEM versions are available in high glucose and low glucose formulations. DMEM requires supplementation with serum, typically 10% Fetal Bovine Serum (FBS), since this medium does not contain proteins, lipids, or growth factors.

    Hanks’ Balanced Salt Solution (HBSS) is an isotonic buffer solution containing inorganic salts and a carbohydrate as an energy source. It is used for various cell culture applications including the short -term maintenance of cells in a non-CO2 environment, washing cells before dissociation or counting, and transporting cells or tissues.

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    Bio-techne – Cultrex UltiMatrix Reduced Growth Factor (RGF) Basement Membrane Extract (BME) 

    Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma. The major components of the baseme...

    Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma. The major components of the basement membrane include laminin, collagen IV, entactin/nidogen, and heparan sulfate proteoglycan. Basement membranes are degraded and regenerated during development and wound healing. They not only support cells and cell layers, but they also play an essential role in tissue organization that affects cell adhesion, migration, proliferation, and differentiation. 

    Cultrex UltiMatrix Reduced Growth Factor (RGF) Basement Membrane Extract (BME) is a soluble form of basement membrane that provides high tensile strength, enhanced levels of entactin/nidogen, elevated protein concentration, and robust clarity and purity. Purified from mouse Engelbreth-Holm-Swarm (EHS) tumor, Cultrex UltiMatrix RGF BME is viscous at 2-8 °C and gels at 37 °C to form a reconstituted basement membrane. Employing an optimized manufacturing process that maximizes purification and solubilization of extracellular matrix protein, Cultrex UltiMatrix RGF BME is a cell scaffolding hydrogel with substantial compositional enhancements and performance benefits for 2D and 3D cell culture applications.

  • Bio-techne – Ella

    Ella performs immunoassays inside a consumable microfluidic Simple Plex assay cartridge. Like a pre‑kitted ELISA, all reagents including matched antibody pairs have been validated. But with Ella, the reagents are pre‑loaded onto a cartridge fo...

    Ella performs immunoassays inside a consumable microfluidic Simple Plex assay cartridge. Like a pre‑kitted ELISA, all reagents including matched antibody pairs have been validated. But with Ella, the reagents are pre‑loaded onto a cartridge for ease of use.

  • Bio-techne – Hana™ and Pala™ 

    Hana and Pala are versatile and gentle benchtop cell sorters and single-cell dispensers.
    Hana is equipped with a 488 excitation laser, and Pala is equipped with 2 excitation lasers, this instrument is capable of detecting and sorting cells u...

    Hana and Pala are versatile and gentle benchtop cell sorters and single-cell dispensers.
    Hana is equipped with a 488 excitation laser, and Pala is equipped with 2 excitation lasers, this instrument is capable of detecting and sorting cells utilizing popular fluorescent molecules and stains. Combine high single-cell dispensing accuracy in both 96 & 384 well plates and gentle bulk sorting capabilities.

  • Bio-techne – Jess 

    ProteinSimple’s Jess™ is a Simple Western™ instrument, an innovative technology from Bio-Techne, that performs capillary-based immunoassays and fully automated Western blot analysis, taking the complexity out of traditional immunoassays like...

    ProteinSimple’s Jess™ is a Simple Western™ instrument, an innovative technology from Bio-Techne, that performs capillary-based immunoassays and fully automated Western blot analysis, taking the complexity out of traditional immunoassays like Western blot and ELISA and filling in their shortcomings.

  • Bio-techne – Luminex® 200™

    The Luminex 200 sets the standard for multiplexing. The ability to use either magnetic or polystyrene beads makes this instrument a popular choice for laboratories needing greater flexibility.

    The Luminex 200 sets the standard for multiplexing. The ability to use either magnetic or polystyrene beads makes this instrument a popular choice for laboratories needing greater flexibility.

  • Bio-techne – MitoBrilliant™

    MitoBrilliant probes have been developed to overcome some common limitations encountered with standard mitochondrial trackers, offering clearer answers to scientific questions. They are next-generation fluorescent stains for the localization and t...

    MitoBrilliant probes have been developed to overcome some common limitations encountered with standard mitochondrial trackers, offering clearer answers to scientific questions. They are next-generation fluorescent stains for the localization and tracking of mitochondria in both live and fixed cells. The range harnesses Janelia Fluor® dye technology, conferring some of the properties that make these widely used dyes, into mitochondrial stains.

  • Bio-techne – N21 & N2 Max Media Supplements

      • N21 MAX Media Supplement (50X) 
        N21-MAX Media Supplement is a serum-free media supplement specially optimized for the long-term culture of central nervous system neurons. N21-MAX Media Supplement has been tested for the viability and growth of E18 rat hippocampal neurons. The supplement is provided as a 50X concentrated solution. 

      • N-2 MAX Media Supplement (100X)
        N-2 MAX Media Supplement is a modification of Bottenstein’s formulation, which provides optimal conditions for neural stem cell expansion. It can be used as a substitute for the N-2 formulation and was optimized for neural cell cultures. The supplement is supplied as a 100X concentrate in deionized water. 

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    Bio-techne – QuantideX® qPCR BCR-ABL IS Kit

    Confidently deliver results with the first  C-certified IVDR chronic myeloid leukaemia (CML) monitoring assay with BCR ABL Major breakpoints (e13a2, e14a2). With direct reporting on the International Scale (IS) and deep clinical sensitivity of 0...

    Confidently deliver results with the first  C-certified IVDR chronic myeloid leukaemia (CML) monitoring assay with BCR ABL Major breakpoints (e13a2, e14a2). With direct reporting on the International Scale (IS) and deep clinical sensitivity of 0.002% (MR 4.7), laboratories can assess the deepest molecular response with unprecedented ease and deliver the results physicians and patients rely on. The QuantideX multiplex assay design and included analysis software render reporting CML monitoring results both accurate and quick, with results in ~4 hours.